Post-transcriptional regulation of alpha-synuclein by leucine-rich repeat kinase 2 and micro-RNAs with implications for Parkinson's disease
One of the major hallmarks of Parkinson’s disease (PD) is the deposition of intracellular Lewy body inclusions. α-Synuclein is a small protein that accumulates and aggregates to form Lewy bodies. Recent studies uncovered variation of α-synuclein mRNA 3’ untranslated region (UTR), but the role of thi...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/14613 |