Pathogenesis of light chain-induced dysfunction in cardiac amyloidosis
Although a rare disease, light chain (LC) amyloidosis (AL) is the most common systemic amyloidosis in developed countries. It is caused by an overproduction of immunoglobulin LC proteins in bone marrow plasma cells. In AL amyloidosis, LCs that are prone to misfolding and insolubility will aggregat...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/14695 |