Shiga toxins and damage-associated molecular patterns leading to endothelial dysfunction

Enterohemorrhagic E. coli (EHEC) infection is a leading cause of acute kidney failure in otherwise healthy children, and a leading cause of foodborne illness with an outsized economic impact from outbreaks. EHEC secrete two Shiga-like toxins (Stx1 and Stx2) which are AB5 holotoxins that inhibi...

Full description

Bibliographic Details
Main Author: Mayer, Chad
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/15270