Shiga toxins and damage-associated molecular patterns leading to endothelial dysfunction
Enterohemorrhagic E. coli (EHEC) infection is a leading cause of acute kidney failure in otherwise healthy children, and a leading cause of foodborne illness with an outsized economic impact from outbreaks. EHEC secrete two Shiga-like toxins (Stx1 and Stx2) which are AB5 holotoxins that inhibi...
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Language: | en_US |
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2016
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Online Access: | https://hdl.handle.net/2144/15270 |