Identification of small molecule modulators of the Hippo tumor suppressor pathway
The Hippo signaling pathway, originally identified in Drosophila melanogaster and later shown to be conserved in mammals, is essential in regulating organ size and maintaining tissue homeostasis. It is now clear that functional inactivation of the Hippo pathway is common in variety of cancers and pr...
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| Language: | en_US |
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2016
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| Online Access: | https://hdl.handle.net/2144/16121 |