Reducing amyloid beta peptide production through regulation of amyloid precursor protein dimerization

Alzheimer’s disease is a progressive and irreversible neurodegenerative disorder characterized by the accumulation of neurotoxic Aβ peptides and subsequent onset of secondary neuropathological changes, including aggregation of hyperphosphorylated tau protein. Aβ peptides, produced through the suc...

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Bibliographic Details
Main Author: Meguerian, Arman
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/16748