Defining YAP/TAZ-dependency in human breast cancer cells

OVERVIEW: Hyperactivation and amplification of the oncogenic transcriptional co-factors YAP and TAZ are common in breast cancer. However, it is unknown if breast cancer cells are dependent on YAP/TAZ for growth and survival. In addition, key transcriptional targets of YAP/TAZ that enable breast canc...

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Bibliographic Details
Main Author: Vakhshoorzadeh, Jasmine
Language:en_US
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/2144/17028