Characterization of a transcript found within the HBS1L-MYB intergenic region and its role in hemoglobin regulation in erythroid cells
Sickle cell disease (SCD) is one of the most common hemoglobinopathies worldwide. It is caused by a homozygous mutation in codon 6 of the beta globin gene (HBB), which leads to polymerization of the variant hemoglobin and sickled red blood cells that obstruct blood vessels and reduce oxygen deliver...
| Main Author: | |
|---|---|
| Language: | en_US |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/2144/26513 |