Examination of the role of envelope directed antibodies on co-receptor usage in HIV-1B infection
HIV-1 primarily utilizes the CCR5 receptor as a co-receptor, but over time, viruses can evolve to use the CXCR4 protein. Changes in the viral envelope V3 loop mediate this switch. The emergence of CXCR4-utilizing viruses has been presumed to occur as a consequence of decreased humoral immunity. We s...
Main Author: | |
---|---|
Other Authors: | |
Language: | en_US |
Published: |
2018
|
Subjects: | |
Online Access: | https://hdl.handle.net/2144/29958 |