Patient derived xenograft models of small-cell lung cancer provide molecular insights into mechanisms of chemotherapy cross-resistance

Small Cell Lung Cancer (SCLC) is a highly aggressive neuroendocrine tumor with a 5% survival rate over 5 years. Though SCLC comprises 13% of all cases of lung cancer the median survival time of 14.5 months has seen little improvement over the last four decades. Standard treatment relies on DNA dama...

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Bibliographic Details
Main Author: Myers, David Thomas
Other Authors: MacNeil, Maryann
Language:en_US
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/2144/31262