Comparison of FLT3 inhibitors with the standard treatment for FLT3-ITD mutated acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy, which is characterized by impaired differentiation and uncontrollable proliferation of myeloid progenitor cells in the bone marrow. One-third of patients with AML have a mutation in the FMS-like tyrosine kinase 3 (FLT3) gene. The...

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Bibliographic Details
Main Author: Argetsinger, Stephanie
Other Authors: MacNeil, Maryann
Language:en_US
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/2144/32984