Multiple testing problems in classical clinical trial and adaptive designs

Multiplicity issues arise prevalently in a variety of situations in clinical trials and statistical methods for multiple testing have gradually gained importance with the increasing number of complex clinical trial designs. In general, two types of multiple testing can be performed (Dmitrienko et al...

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Bibliographic Details
Main Author: Deng, Xuan
Other Authors: Chang, Mark
Language:en_US
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/2144/33080