Biophysical analysis and NMR structural characterization of the binding between peptidomimetic drug CN2097 and scaffolding protein PSD-95
BACKGROUND: At the postsynaptic membrane of neurons there is a dense network of proteins called the postsynaptic density (PSD). One such protein is the postsynaptic density protein 95 (PSD-95), which functions as a molecular scaffold for forming protein complexes at the PSD. PSD-95 is composed of...
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| Language: | en_US |
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2019
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| Online Access: | https://hdl.handle.net/2144/36537 |