An ERK-dependent signaling pathway regulated by miRs contributes to an aging-related decrease in smooth muscle contractility by inhibiting caldesmon phosphorylation
This project focused on extracellular signal-regulated kinase (ERK) and focal adhesion proteins related to ERK activity, and found a novel signaling pathway contributing to aging-related defects in smooth muscle contractility. Previous members of our lab have used ERK inhibitors to demonstrate the...
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| Language: | en_US |
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2019
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| Online Access: | https://hdl.handle.net/2144/37004 |