Histone H4 activates neutrophils alone or with influenza A virus, unless countered by C-reactive protein and surfactant protein-D

Extracellular histones have been implicated as a cause of tissue inflammatory injury in a variety of disorders including sepsis, lung and liver diseases. However, little is known about their interactions with neutrophils and how this might contribute to injury. We used human neutrophils isolated fro...

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Bibliographic Details
Main Author: Hsieh, I-Ni
Other Authors: Hartshorn, Kevan L.
Language:en_US
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/2144/38562