Role of HIV-1 Vpr in regulation of expression of unintegrated viral DNA
Vpr, one of the four accessory proteins in HIV-1, is expressed in all primate lentiviruses, and has been shown to facilitate viral replication through degradation of various host factors in a DCAFCrl4 E3 ubiquitin ligase dependent manner and induce a G2/M cell cycle arrest. But the underlying mechan...
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| Language: | en_US |
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2019
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| Online Access: | https://hdl.handle.net/2144/38746 https://orcid.org/0000-0001-7238-0805 |