Role of HIV-1 Vpr in regulation of expression of unintegrated viral DNA
Vpr, one of the four accessory proteins in HIV-1, is expressed in all primate lentiviruses, and has been shown to facilitate viral replication through degradation of various host factors in a DCAFCrl4 E3 ubiquitin ligase dependent manner and induce a G2/M cell cycle arrest. But the underlying mechan...
Main Author: | |
---|---|
Other Authors: | |
Language: | en_US |
Published: |
2019
|
Subjects: | |
Online Access: | https://hdl.handle.net/2144/38746 https://orcid.org/0000-0001-7238-0805 |