Nanoparticles modulate lysosomal acidity and autophagic flux to rescue cellular dysfunction

Autophagy is a critical cellular maintenance machinery in cells, and prevents the accumulation of toxic protein aggregates, organelles or lipid droplets through degradation via the lysosome. In macro-autophagy, autophagosome first engulfs around aggregates or cellular debris and subsequently fuses w...

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Bibliographic Details
Main Author: Zeng, Jialiu
Other Authors: Grinstaff, Mark W.
Language:en_US
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/2144/41021