Role of mTORC1 in lysosomal localization in glucagon secretion

BACKGROUND: Elevation of glucagon levels and increase in alpha-cell mass are associated with states of hyperglycemia in diabetes. However, little is known about the mechanisms that control glucagon secretion and alpha-cell mass expansion in normal or diabetogenic conditions. Glucagon is secreted dur...

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Bibliographic Details
Main Author: Barrios, Alexia
Other Authors: Garcia-Diaz, Jesus Fernando
Language:en_US
Published: 2020
Subjects:
p18
Online Access:https://hdl.handle.net/2144/41123