Computational approaches to discover and characterize transcription regulatory complex binding from protein-binding microarray-based experiments

Gene regulation is controlled by DNA-bound complexes of transcription factors (TFs) and indirectly recruited transcriptional cofactors (COFs). Understanding how and where these TF-COF complexes bind in the genome is fundamental to our understanding of the role of cis-regulatory elements (CREs) in ge...

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Bibliographic Details
Main Author: Bray, David
Other Authors: Siggers, Trevor W.
Language:en_US
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/2144/41910