Transcriptional wiring of immune gene regulatory networks and rewiring by transcription factor isoforms
Gene regulatory networks (GRNs) are central to every biological process from development to disease. GRNs are mediated through the activities of transcription factors (TFs), which interact in a sequence-specific manner with their target DNA elements to drive gene expression. In this thesis, two main...
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Language: | en_US |
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2021
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Online Access: | https://hdl.handle.net/2144/43253 |