Macrocycles as inhibitors of protein-protein interactions
Among the many drugs that have been developed from natural products, macrocyclic compounds (MCs) – compounds containing a ring of 11 or more atoms – are a recurring chemotype. It is not fully understood how large MCs can have utility as drugs, despite violating conventional notions of druglikness. I...
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| Language: | en_US |
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2021
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| Online Access: | https://hdl.handle.net/2144/43255 |