Determining transcription factor interactions with the add domain of DNA methyltransferases DNMT3A and DNMT3B

To control gene expression, transcription factors (TFs) bind to DNA and recruit regulatory cofactors (COFs) that mediate diverse effects on chromatin, such as DNA and histone modifications. To better help understand TF and COF interactions, our lab has been developing the nuclear extract protein-bin...

Full description

Bibliographic Details
Main Author: Wadden, Evan
Other Authors: Siggers, Trevor
Language:en_US
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/2144/43365