CD74 is a novel gene which facilitates resistance of tumors to current EGFR tyrosine kinase inhibitor therapy in non-small cell lung cancer patients
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) are highly effective therapies for sub-populations of non-small cell lung cancers. Specific mutations have been identified in the EGFR gene such as L858R which overstimulate cell pathways that lead to tumor growth. All tumors e...
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| Language: | en_US |
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2021
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| Online Access: | https://hdl.handle.net/2144/43520 |