How does mitochondrial heteroplasmy affect cell proliferation?

How does mitochondrial heteroplasmy affect cell proliferation?

Mitochondrial mutations and heteroplasmy have been associated with disease states that result from inadequate cellular energy production. As mitochondrial DNA (mtDNA) encodes many of the polypeptides involved in oxidative phosphorylation (OXPHOS), mtDNA mutations may lower energy production which...

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Bibliographic Details
Main Author: Sutton, Selina Kaye
Language:en
Published: University of Canterbury. Biological Sciences 2008
Subjects:
mitochondria
DNA mutation
disease
oxidative phosphorylation
cancer cell line
cell proliferation
population doubling time
Online Access:http://hdl.handle.net/10092/1306

Internet

http://hdl.handle.net/10092/1306

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