Molecular Switches: The Design, Synthesis and Biological Applications of Photoactive Enzyme Inhibitors

This thesis examines the design, synthesis and biological applications of a series of inhibitors which incorporate an azobenzene photoswitch, a peptidyl backbone and a trifluoromethyl ketone warhead. The photoswitch can be isomerised by irradiation with UV or visible light and has been employed to m...

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Bibliographic Details
Main Author: Alexander, Nathan Austin
Language:en
Published: University of Canterbury. Chemistry 2008
Subjects:
Online Access:http://hdl.handle.net/10092/1314