Development of macrocyclic β-strand calpain cysteine protease inhibitors

The work in this thesis reports studies directed to developing a calpain cysteine protease inhibitor that could be of value in slowing cataract development in humans. The work focuses on the development of macrocyclic compounds which can have advantages over acyclic compounds due to their resistance...

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Bibliographic Details
Main Author: Chen, Hongyuan
Language:en
Published: University of Canterbury. Chemistry 2011
Subjects:
Online Access:http://hdl.handle.net/10092/5582