Nitrogenous heterocycles : modulation of chemical properties, and applications to synthetic and medicinal chemistry.
This thesis examines ways in which the chemical reactivity of benzimidazole-, pyrrole- or pyrrolizinone-based heterocycles can be modulated. The latent reactivity of these systems has been used to develop enzyme inhibitors, antitumour compounds and a novel amino acid derivatisation technique. Chapt...
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Language: | en |
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University of Canterbury. Chemistry
2011
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Online Access: | http://hdl.handle.net/10092/5650 |