Mechanisms of 7,8-dihydroneopterin protection of macrophages from cytotoxicity

Gamma-interferon stimulates human macrophages to produce of 7,8-dihydroneopterin (7,8-NP). 7,8-NP and its oxidation product neopterin are excellent inflammatory markers for a variety of chronic conditions, including atherosclerosis. The biological significance of 7,8-NP in atherosclerosis is not ful...

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Bibliographic Details
Main Author: Shchepetkina, Anastasia
Language:en
Published: University of Canterbury. Biological Sciences 2013
Subjects:
Online Access:http://hdl.handle.net/10092/8181