Hierarchical Association of Subcomplexes Drives pre-rRNA Folding during Ribosome Biogenesis in <i>Saccharomyces cerevisiae</i>
Construction of eukaryotic ribosomes requires at least 180 assembly factors. These proteins are thought to drive forward the progressive folding and processing of pre-rRNAs, and binding of ribosomal proteins. Initial characterizations have revealed in which steps of pre-rRNA processing most of thes...
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Format: | Others |
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Research Showcase @ CMU
2013
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Online Access: | http://repository.cmu.edu/dissertations/271 http://repository.cmu.edu/cgi/viewcontent.cgi?article=1274&context=dissertations |