Biophysical Characterization of the Dynamic Regulation of Chromatin Structure and Rheology in Human Cell Nuclei

Out of the growing body of evidence demonstrating the role of higher-order chromatin organization within the nucleus in regulating the functions of the linear sequence of DNA emerges the genome as a physical entity. DNA packs into hierarchical levels of chromatin condensation, which then tailor acce...

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Bibliographic Details
Main Author: Spagnol, Stephen
Format: Others
Published: Research Showcase @ CMU 2015
Subjects:
Online Access:http://repository.cmu.edu/dissertations/526
http://repository.cmu.edu/cgi/viewcontent.cgi?article=1526&context=dissertations