The Role of CtIP in BRCA1-Mediated Tumor Suppression
Familial cases of breast and ovarian cancer are often attributed to germline mutations of the BRCA1 tumor suppressor gene. Although the mechanisms of BRCA1 tumor suppression are poorly understood, its protein product has been implicated in multiple aspects of the DNA damage response. As such, BRCA1...
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Language: | English |
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2012
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Online Access: | https://doi.org/10.7916/D82J68Z9 |