Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5
This thesis explores the role of mechanochemistry in two biological systems. The first system investigated involves cargo transport along microtubule filaments by Kinesin 1. A gating mechanism is needed to coordinate ATP binding to the two catalytic domains within Kinesin 1 in order to prevent simul...
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| Language: | English |
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2011
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| Online Access: | https://doi.org/10.7916/D83B66HW |