Accurate and Sensitive Quantification of Protein-DNA Binding Affinity

Transcription factors control gene expression by binding to genomic DNA in a sequence-specific manner. Mutations in transcription factor binding sites are increasingly found to be associated with human disease, yet we currently lack robust methods to predict these sites. Here we developed a versatil...

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Bibliographic Details
Main Author: Rastogi, Chaitanya
Language:English
Published: 2017
Subjects:
Online Access:https://doi.org/10.7916/D86T104B