Probing static disorder in protein unfolding and chemical reactions by single-molecule force spectroscopy
The work presented in this dissertation focuses on the kinetics of biomolecular reactions under mechanical force, including protein unfolding and disulfide-bond reduction, probed at the single-molecule level. The advent of single-molecule force spectroscopy has allowed the direct measure of force-de...
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| Language: | English |
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2011
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| Online Access: | https://doi.org/10.7916/D8862PN4 |