Insights into MYC biology through investigation of synthetic lethal interactions with MYC deregulation
MYC (or c-myc) is a bona fide "cancer driver" oncogene that is deregulated in up to 70% of human tumors. In addition to its well-characterized role as a transcription factor that can directly promote tumorigenic growth and proliferation, MYC has transcription-independent functions in vital...
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| Language: | English |
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2014
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| Online Access: | https://doi.org/10.7916/D8FF3QH3 |