Transcriptional control of tumor suppressor genes in cancer

An important hallmark of cancer is the inactivation of tumor suppressor genes. The most common genetic alteration in cancer is the mutation of the TP53 gene occurring in about half of all cancers, but very little progress has been made on how to therapeutically target the signaling defects in these...

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Bibliographic Details
Main Author: Pappas, Kyrie Jean
Language:English
Published: 2017
Subjects:
Online Access:https://doi.org/10.7916/D8MW2NQM