On Identifying Rare Variants for Complex Human Traits

This thesis focuses on developing novel statistical tests for rare variants association analysis incorporating both marginal effects and interaction effects among rare variants. Compared with common variants, rare variants have lower minor allele frequencies (typically less than 5%), and hence tradi...

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Bibliographic Details
Main Author: Fan, Ruixue
Language:English
Published: 2015
Subjects:
Online Access:https://doi.org/10.7916/D8N29VT4