From the End to the Middle: Regulation of Telomere Length and Kinetochore Assembly by the RNR Inhibitor SML1
Accurate DNA replication is essential for proper cellular growth and requires an adequate and balanced supply of dNTPs. In Saccharomyces cerevisiae, de novo dNTP synthesis through nucleotide reduction by the Ribonucleotide reductase (RNR) enzyme is the sole method of production. Hence, RNR activitit...
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| Language: | English |
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2012
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| Online Access: | https://doi.org/10.7916/D8P2756B |