The Regulation of PREX2 by Phosphorylation
Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3)-dependent RAC exchanger 2 (PREX2) is a guanine nucleotide exchange factor (GEF) for the Ras-related C3 botulinum toxin substrate 1 (RAC1) GTPase. As a GEF, PREX2 facilitates the exchange of GDP for GTP on RAC1. GTP bound RAC1 then activates its...
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| Language: | English |
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2015
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| Online Access: | https://doi.org/10.7916/D8PN94WH |