Phosphorylation dependent structural function of DNA-PKcs in DNA repair and hematopoiesis

Genomic stability is essential for maintaining cellular function and preventing oncogenic transformation. DNA double strand breaks (DSBs) are the most severe form of DNA damage. Classical non-homologous end joining (cNHEJ) is one of two major DSB repair pathways in mammalian cells. During lymphocyte...

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Bibliographic Details
Main Author: Crowe, Jennifer Lauryn
Language:English
Published: 2018
Subjects:
Online Access:https://doi.org/10.7916/D8QR68MS