Quantitative and dynamic analysis of the focused-ultrasound induced blood-brain barrier opening in vivo for drug delivery

The rate limiting factor for the treatment of neurodegenerative diseases is the blood-brain barrier (BBB), which protects the brain microenvironment from the efflux of large molecules, and thus it constitutes a major obstacle in therapeutic drug delivery. All state-of-the-art strategies to circumven...

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Bibliographic Details
Main Author: Samiotaki, Gesthimani
Language:English
Published: 2015
Subjects:
Online Access:https://doi.org/10.7916/D8SN07VT