Novel Roles of Ataxia Telangiectasia Mutated (ATM) in DNA Repair and Tumor Suppression
Mammalian cells possess a variety of different DNA repair pathways, which work together to safeguard genomic integrity upon encountering different types of DNA damage. Among all lesions, DNA double-strand breaks (DSBs) are most toxic and, if left unrepaired, results in loss of genetic information an...
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| Language: | English |
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2015
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| Online Access: | https://doi.org/10.7916/D8X34X6T |