Loop Prediction and Homology Modeling with High Resolution

Three-dimensional (3D) structure of a protein is essential as the guidance of structure-based drug dis-covery. To achieve robust homology modeling with atomic-level accuracy, reliable loop predictions are required. Here, a novel hierarchical protocol of Protein Local Optimization Program (PLOP) is...

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Bibliographic Details
Main Author: Xu, Tianchuan
Language:English
Published: 2020
Subjects:
Online Access:https://doi.org/10.7916/d8-1dqz-y485