Elucidating the abilities of MDM2, MDMX and p21 to regulate ferroptosis
In this thesis, I have explored the role of three genes related to p53, namely p21, MDM2 and MDMX, in regulating ferroptosis, a form of non-apoptotic cell death. Ferroptosis, an iron-dependent mechanism that leads to cell death due to lipid peroxidation, has a large potential to be used as a cancer...
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| Language: | English |
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2020
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| Online Access: | https://doi.org/10.7916/d8-es1c-z783 |