Mutagenic Repair Outcomes of DNA Double-Strand Breaks
DNA double strand breaks (DSB) are cytotoxic lesions that can lead to genome rearrangements and genomic instability, which are hallmarks of cancer. The two main DSB repair pathways are non-homologous end joining and homologous recombination (HR). While HR is generally highly accurate, it has the pot...
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| Language: | English |
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2021
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| Online Access: | https://doi.org/10.7916/d8-w9jx-ke41 |