Role of intestinal trefoil factor in gastric carcinogenesis.
Induction of ITF expression significantly enhanced invasion of Rat-2 (1.8-folds) without promoting proliferation. The increase in invasiveness was accompanied by an upregulation of beta-catenin (18.0%) and MMP-9 (67.8%), and downregulation of E-cadherin (29.7%) and TIMP-1 (34.7%). Silencing ITF in M...
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| Format: | Others |
| Language: | English Chinese |
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2005
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| Online Access: | http://library.cuhk.edu.hk/record=b6074064 http://repository.lib.cuhk.edu.hk/en/item/cuhk-343693 |