Development of new markers and approaches for the detection of fetal DNA in maternal plasma.

Another attempt was made to identify CpG-rich paralogues on chromosome 21 for dosage analysis. Methylation profiles of 14 paralogous CpG-rich clusters were screened by bisulfite genomic sequencing and/or combined bisulfite restriction analysis. One of the paralogue pairs showed similar differential...

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Bibliographic Details
Other Authors: Lun, Miu Fan.
Format: Others
Language:English
Chinese
Published: 2008
Subjects:
DNA
Online Access:http://library.cuhk.edu.hk/record=b6074589
http://repository.lib.cuhk.edu.hk/en/item/cuhk-344222