cTnI N-Terminal deletion: an agent for rescuing restrictive cardiomyopathy, a disease caused by mutations of Cardiac Troponin I
Restrictive cardiomyopathy (RCM) is represented in part by left ventricular stiffness and diastolic dysfunction. Missense mutations of the cardiac troponin I (cTnI) gene cause idiopathic RCM. These mutations are located in the C-terminus of cTnI and affect cardiac relaxation. Transgenic mouse mod...
| Other Authors: | |
|---|---|
| Format: | Others |
| Language: | English |
| Published: |
Florida Atlantic University
|
| Subjects: | |
| Online Access: | http://purl.flvc.org/fau/fd/FA00004196 http://purl.flvc.org/fau/fd/FA00004196 |