Cleavage of brain glutamic acid decarboxylase 65 by calpain under pathological conditions

Cleavage of brain glutamic acid decarboxylase 65 by calpain under pathological conditions

Brain glutamic acid decarboxylase 65 (GAD65) catalyzes the rate-limiting step in the biosynthesis of the major inhibitory neurotransmitter-amino butyric acid (GABA) from the substrate L-glutamic acid. Severe lapse in GABA neurotransmission is one of the etiologies documented in the manifestation of...

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Bibliographic Details
Other Authors: Buddhala, Chandana
Format: Others
Language:English
Published: Florida Atlantic University
Subjects:
Glutamic acids > Antagonists
Proteolytic enzymes > Research
Cellular signal transduction
Calpain
Glutamic acid > Metabolism
Online Access:http://purl.flvc.org/FAU/3342053

Internet

http://purl.flvc.org/FAU/3342053

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