Synthesis of multisubstituted halo-olefins via Pd-catalyzed cross-coupling reactions : applications in nucleoside chemistry
The enzyme S-adenosyl-L-homocysteine (AdoHey) hydrolase effects hydrolytic cleavage of AdoHcy to adenosine (Ado) and L-homocysteine (Hcy). The cellular levels of AdoHcy and Hcy are critical because AdoHcy is a potent feedback inhibitor of crucial transmethylation enzymes. Also, elevated plasma level...
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FIU Digital Commons
2006
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| Online Access: | http://digitalcommons.fiu.edu/etd/1287 http://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=2422&context=etd |