Novel nucleoside analogues with bases modified with (β-halo)vinyl sulfone or β-keto sulfone as probes to study RNA/DNA-Proteins interactions
The C-5 modified pyrimidine analogues are well-known anticancer and antiviral drugs which underscore further development of novel probes to study their physical, chemical, and biological properties. In my dissertation the syntheses and properties of (β-halo)vinyl sulfone and/or (β-keto)sulfone analo...
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FIU Digital Commons
2017
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Online Access: | http://digitalcommons.fiu.edu/etd/3372 http://digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=4334&context=etd |